The Best Extraction Methods of Wet and Dry Papaja (Carica papaja L.) Seed as Anthelmintics Effect on Ascardia galli

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The Best Extraction Methods of Wet and Dry Papaja (Carica papaja L.) Seed as Anthelmintics Effect on Ascardia galli

http://repository.uhamka.ac.id/915/

Gusmayadi, Inding

Papaya seed in previous research is known has an effect of anthelmintic on Ascardia
galli, but the effect of papaya seed just by traditional method i.e. boiling in water. To get
the effective extraction methods, it still needs to be done many kinds of extraction methods
of papaya seed, to know which one is the best. Methods of extraction in this research were
maceration, soxhletation, and ultrasonic digestion. We used two kinds of papaya seed: wet
and dry, using solvent: water, 70% ethanol, and n-hexane. Data of anthelmintic activity
were percentage of worm death, LD50, and relative potential to pyrantel pamoate as positive
control. The result showed that the best extraction method of papaya seed which had
highest in vitro effect on Ascardia galli worm was maceration method with 70% ethanol as
solvent of wet papaja seed. It killed 60% of worm with LD50 9.36 mg and its relative
potential is 0.66 times pyrantel pamoate.

http://repository.uhamka.ac.id/915/1/Inding%20Gusmayadi%20-%20Proceeding%20ICPSP%20-%20Buku%20%287-11%29.pdf

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